Tag Archives: peptide bonds

Biological Effects Of Peptides

peptide bonds

Peptides are biological compounds which appear like short chains of two or more amino acids connected together by amino bonds. They are similar to proteins but differ slightly in size and structure. Proteins are bigger in size with a more well-defined structure. Intensive research is happening in the field of peptides and researchers have already found out methods to create synthetic peptides. There are many online sources from where you can purchas peptides for sale. GHRP-2, GHRP-6, GRF 1-44, MT-1, MT-2, etc. are some of the common synthetic peptides.

Considering the information available from various articles published in scirp.org, we have come to know that peptides are widely tested on animals and are known to produce certain biological effects in them. Let us have a look at such effects of peptides, especially Melanotan (MT-1 and MT-2).

Scientific details
MT-1 and MT-2 are synthetic versions of the alpha-Melanocyte Stimulating Hormone (MSH) which is biologically produced by the pituitary gland. MT-1 is also known as Afamelanotide. Alpha-MSH makes use of melanocortin receptors to exercise its effects. The molecular weight of MT-1 is 1646.88, and that of MT-2 is 1024.2. These peptides were first synthesized by researchers in Arizona University.

When research was carried out using these peptides which are the synthetic version of the natural ones, they have shown their impact on certain biological functions of animals such as rats and rabbits. Here are the details of the functions which were affected in animals.

Melanogenesis
Melanogenesis is the scientific term for the production of melanin by cells. Recent studies using the peptide Melanotan conducted on rodents, and other animals showed high secretion of melanin when their skin was exposed to Ultraviolet rays. Studies have shown that MT-2 activates the central melanocortin which in turn, stimulates melanogenesis. The secreted melanin acted as a protection against harmful ultraviolet rays and ultimately safeguarded the exposed animals. More studies are being conducted on animals to find out the efficiency of synthetic peptides.

Appetite suppression
The peptide Melanotan 2, which is an advanced version of Melanotan 1 was used in animals such as rats and rabbits and was found to have appetite suppressing properties. The appetite for food was greatly reduced in tested animals. Melanotan 2 has shown more effectiveness compared to Melanotan 1.

Aphrodisiac properties
Aphrodisiac properties refer to attributes stimulating sexual desire. Tests conducted on male and female rats and rabbits showed increased sexual behavior in these animals. Female rabbits showed traits such as hops, ear wiggling, solicitation and other receptive behaviors. The experimental results proved a large reduction of receptors such as melanocortin receptor 3 and melanocortin receptor 4 when peptides were used in animals.

All the effects discussed above have been found in animals and are not proved in humans. Research in this field is never stopping. Peptide research has received a lot of focus recently. Hence this field attracts researchers. Numerous researchers are storming their brains on studies and experiments about peptides. Research is growing fast, and new data are emerging day by day. Let us hope for more useful knowledge coming up in this field.